Cell signaling: principles and mechanisms

Introduction to cell signaling

Principles and mechanisms of protein interactions

Signaling enzymes and their allosteric regulation

Role of post-translational modifications in signaling

Subcellular localization of signaling molecules

Second messengers: small signaling mediators

Membranes, lipids, and enzymes that modify them

Information transfer across the membrane

Regulated protein degradation

Modular architecture and evolution of signaling proteins

Information processing by signaling devices and networks

How cells make decisions

Methods for studying signaling proteins and networks.